Sachgebiete

Beschreibung:

336 S. Fadengehefteter Originalpappband.

Bemerkung:

Tadellos, nahezu ohne Gebrauchsspuren. - Inhalt: Genetics and the Epidemiology of Leukemia in Children: Epidemiology of Acute Childhood Leukemia / Julie A. Ross, Kimberly J. Johnson, Logan G. Spector, and John H. Kersey -- Biology of Pediatrie Leukemia: The Biology of Acute Lymphoblastic Leukemia / William L. Carroll, Mignon Loh, Andrea Biondi, and Cheryl Willman -- Biology of Acute Myeloid Leukemia / Robert J. Arceci and Soheil Meshinchi -- Treatment Considerations in Childhood Leukemia: Classification and Treatment of Acute Lymphoblastic Leukemia / Stephen P. Hunger, Valentino Conter, Elizabeth A. Raetz, Maria Grazia Valsecchi, and Guenter Henze -- Treatment of Acute Myeloid Leukemia / Brenda Gibson, John Perentesis, Todd A. Alonzo, and -- Gertjan J.L. Kaspers -- The Impact of Pharmacogenetics and Pharmacogenomics on Childhood Leukemia: Pharmacogenetic and Pharmacogenomic Considerations in the Biology and Treatment of Childhood Leukemia / Jun J. Yang, Parinda A. Mehta, Mary V. Relling, and Stella M. Davies -- The Potential Role of Biologically Targeted Therapy for Childhood Leukemia: Promising Targeted Agents / Patrick Brown, Gregory H. Reaman, Nita L. Seibel, and Pamela Kearns -- Strategies for New Agent Development and Clinical Trial Considerations / Malcolm Smith, Meenakshi Dévidas, Keith Wheatley, Richard B. Lock, and Sally Hunsberger -- Late Effects of Leukemia and Its Therapy: Late Sequelae in Children with Acute Lymphoblastic Leukemia: Impact on Long-Term Survival and Quality of Life / Joseph P. Neglia, Maura O'Leary, and Smita Bhatia -- Acute Toxicities, Late Sequelae, and Quality of Survivorship in Children with Acute Myeloid Leukemia: -- The Impact of Allogeneic Stem Cell Transplant / Julianne Byrne, John Horan, and H. Stacy Nicholson -- Psychosocial Implications of Acute Leukemia Diagnosis and Treatment for Children and Families: Appreciation and the Interdisciplinary Management of the Psychosocial Impact of Leukemia on Children -- and Their Families / Anne L. Angiolillo, Momcilo Jankovic, Riccardo Haupt, Kathleen Ruccione, E. Anne Lown, and Robert B. Noll -- Global Strategies to Improve Leukemia Care and Outcome for Children: Improved Outcome for Children with Acute Leukemia: How to Address Global Disparities / Yaddanapudi Ravindranath, Hans Peter Wagner, Giuseppe Masera, Fulgencio Baez, Anjo.J.P. Veerman, Jacqueline Cloos, Raul Ribeiro, and Gregory H. Reaman -- Perspectives and Future Direction: Future Challenges and Opportunities to Improve Outcomes for Children with Leukemia / Gregory H. Reaman and Franklin O. Smith. - This book is a comprehensive and up-to-date compendium on all aspects of childhood acute lymphoblastic and acute myeloid leukemia, which together constitute the most frequent cancer in the pediatric age group. After introductory chapters on the epidemiology and biology of pediatric leukemia, treatment considerations are extensively reviewed, with emphasis on the use of risk-adjusted treatment approaches. Promising targeted agents are discussed, and strategies for the development of new agents are appraised. The late effects of leukemia and its therapy are then considered in depth, with due attention to management of the psychosocial impact of the disease. Finally, global strategies to improve leukemia care and outcome are reviewed, and future directions discussed. The authors are internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric leukemia and will prove invaluable to specialists, generalists, and trainees alike. (Verlagstext). ISBN 9783642137808